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dc.contributor.authorGyongy, I.
dc.contributor.authorDavies, A.
dc.contributor.authorGallinet, B.
dc.contributor.authorDutton, N. A. W.
dc.contributor.authorDuncan, R. R.
dc.contributor.authorRickman, C.
dc.contributor.authoret al.
dc.date.accessioned2021-12-09T14:00:20Z
dc.date.available2021-12-09T14:00:20Z
dc.date.issued2018
dc.identifier.citationOptics Express, vol. 26 (3), pp. 2280-2291, Feb 2018.
dc.identifier.urihttps://yoda.csem.ch/handle/20.500.12839/230
dc.description.abstractSingle-photon avalanche photodiode (SPAD) image sensors offer time-gated photon counting, at high binary frame rates of >100 kFPS and with no readout noise. This makes them well-suited to a range of scientific applications, including microscopy, sensing and quantum optics. However, due to the complex electronics required, the fill factor tends to be significantly lower (< 10%) than that of EMCCD and sCMOS cameras (>90%), whilst the pixel size is typically larger, impacting the sensitivity and practicalities of the SPAD devices. This paper presents the first characterisation of a cylindrical-shaped microlens array applied to a small, 8 micron, pixel SPAD imager. The enhanced fill factor, approximate to 50% for collimated light, is the highest reported value amongst SPAD sensors with comparable resolution and pixel pitch. We demonstrate the impact of the increased sensitivity in single-molecule localisation microscopy, obtaining a resolution of below 40nm, the best reported figure for a SPAD sensor. (c) 2018 Optical Society of America
dc.subjectfluorescence, cameras, imager, Optics
dc.titleCylindrical microlensing for enhanced collection efficiency of small pixel SPAD arrays in single-molecule localisation microscopy
dc.typeJournal Article
dc.type.csemdivisionsDiv-R
dc.type.csemresearchareasPhotonics
dc.identifier.doihttps://doi.org/10.1364/oe.26.002280


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