Welcome to YODA – Open Digital Archive for CSEM
The YODA archive gives access to CSEM's publications, such as its annual reports and brochures. For technical papers such as scientific publications, bibliographic information is provided, along with the full paper where this is possible.
This comprehensive database is part of CSEM's Open Access Publishing policy. For further information refer to the YODA support guide or contact repository@csem.ch.
Recent Submissions
Item Urine – Non-invasive Matrix in Human Biomonitoring(2022)Urine is a non-invasive source of liquid biopsy samples and in addition, urine-based tests are more advantageous than clinicopathological parameters for periodic monitoring. We developed an easy-to-use urine analyzer system addressing the need for quantitative and costless multi-parameter urine analysis for both, relevant clinical environments as screening methods, and at home as informative.Item Mid-IR QCL-powered Modular Platform for Contactless, Real-time Metabolite Monitoring(2023)In the field of bioprocesses, noncontact, real-time metabolite monitoring is increasingly in demand, as it plays a key role in optimizing production processes, ensuring product quality, and improving the efficiency and reliability of biomanufacturing operations. Based on the recent advancement in the field of mid-IR vibrational spectroscopy, leveraging Quantum Cascade Lasers (QCLs) and nanophotonic structures, the concept of a novel modular sensing platform is presented which facilitates continuous, real-time metabolite quantification in cell culture media.Item SUMON – Disposable System for Sensors Monitoring(2023)SUMON covers the realization of multiple technology bricks including various types of sensors (ionic, enzymatic, and bioassays) having a small sensing area, electro-chemical AFE dedicated to the sensors, a demonstration at the brick-level including the management of data and the related security.Item CRISPR-Cas Systems(2023)Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based diagnostics have emerged as promising tool to revolutionize molecular diagnostics. Despite notable progress, challenges exist in utilizing CRISPR platforms for point-of-care (POC) applications, such as amplification steps and a focus on non-nucleic acids target detection. We propose an innovative approach, exploiting a DNA circuit, to detect antibodies with an amplification-free CRISPR-based assay.Item Portable Fluorescence Biosensing System for Low-cost, Quantitative, and Multiplexed Allergen Screening(2023)CSEM developed a miniaturized fluorescence multisensing system for the rapid identification of immune-mediated responses, enabling the simultaneous detection of multiple allergens in just one hour. The portable solution eliminates painful skin tests and time-consuming lab procedures towards efficient allergy diagnosis and timely treatment. CSEM's solution consists of a microfluidic chip and an automated processing system to identify allergy-specific IgEs in serum by using fluorescence-labeled antibodies. At the core of this advancement lies a user-friendly portable optical reader that can be easily integrated into a doctor’s daily routine.
Communities in YODA
Select a community to browse its collections.