GaSb Swept-Wavelength Lasers for Biomedical Sensing Applications

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Vizbaras, Augustinas
Šimonytė, Ieva
Droz, Serge
Torcheboeuf, Nicolas
Miasojedovas, Arūnas
Trinkūnas, Augustinas
Bučiūnas, Tadas
Dambrauskas, Žilvinas
Gulbinas, Antanas
Boiko, Dmitri L.
Infrared spectral range between 1.7 and 2.5 ?m is of particular interest for biomedical sensing applications due to the presence of first overtone C-H stretch and a combination of stretch and bending vibrations of C-H, N-H, and O-H bonds. These vibrations are molecule specific and can be used to selectively sense important biomolecules such as glucose, lactate, urea, ammonia, serum albumin, etc. In this paper, we review recent developments of swept-wavelength lasers based on GaSb type-I gain-chip technology, their key performance parameters for spectroscopy applications and provide experimental data on spectroscopic sensing of the key biomolecules both in synthetic solutions as well as whole blood.
Publication Reference
IEEE Journal of Selected Topics in Quantum Electronics, vol. 25 (6), pp. 1-12