Aptamer-based Electrochemical Sensor for the Monitoring of Carbamazepine in Freshwater Systems
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Author
Pierrick, Clément
Alba, Finelli
Xavier, Lefèvre
Saleem, Kahn
Alexandra, Beard
Raphaël, Pugin
Abstract
Carbamazepine (CBZ) is an active compound in commonly used drug and is highly durable in the environment, particularly in wastewater, which raises concerns about potential risks to animals and humans. We present an aptamer-based electrochemical sensor labelled with a redox probe which conformational change upon binding event is recorded by square-waved voltammetry. The electro-chemical sensor operated in concentrations range from 2.5 pM to 250 μM in buffer. This technology provides a potential method to enable the monitoring of CBZ in treated water.
Publication Reference
https://www.ama-science.org/assets/Eurosensors/2024/EUROSENSORS-XXXVI.pdf
Year
2024-09-01