Versatile laser for two-photon excitation in digital diagnostics
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Author
Boiko, D.L.
Drs, J.
Flückiger, P.
Oeschger, S.
Boust, S.
Krakowski, M.
DOI
Abstract
In the realm of biomedical research, the limitations of current light sources hinder progress in crucial areas. Conventional instruments confine two-photon microscopy and time-resolved detection to specialized labs, impeding breakthroughs in cancer research and diagnostics. The EU-funded HILIGHT project aims to overcome existing limitations and pave the way for transformative advancements in biomedical and healthcare applications. Specifically, it will introduce a miniaturized optical pulse burst source and cutting-edge sensing technology. Two key applications underscore its potential impact: instantaneous digital histopathology and cancer research. With a consortium comprising academic industrial and research partners from five European countries (III-V lab, CSEM, VivaScope GmbH, FBK and Brunel University of London), the collaborative effort is expected to facilitate faster diagnoses and more effective treatments[1]. CSEM plays a dual role in the project, split across two core areas: • Overall system throughput analysis and subsystem requirements definitions. • Delivery and integration of semiconductor mode-locked laser and electronics for confocal scanning digital histopathology microscope.
Publication Reference
CSEM Scientific and Technical Report 2025, p. 35–36
Year
2025