CRISPR-Cas Systems
| dc.contributor.author | Del Giovane, S. | |
| dc.contributor.author | Migliorelli, D. | |
| dc.contributor.author | Burr, L. | |
| dc.contributor.author | Altug, H. | |
| dc.contributor.author | Porchetta, A. | |
| dc.date.accessioned | 2024-10-02T12:12:45Z | |
| dc.date.available | 2024-10-02T12:12:45Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based diagnostics have emerged as promising tool to revolutionize molecular diagnostics. Despite notable progress, challenges exist in utilizing CRISPR platforms for point-of-care (POC) applications, such as amplification steps and a focus on non-nucleic acids target detection. We propose an innovative approach, exploiting a DNA circuit, to detect antibodies with an amplification-free CRISPR-based assay. | |
| dc.identifier.citation | CSEM Scientific and Technical Report 2023, p. 84. | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12839/1520 | |
| dc.title | CRISPR-Cas Systems | |
| dc.type | CSEM Report | |
| dc.type.csemdivisions | BU-R | |
| dc.type.csemresearchareas | Tools for Life Sciences |