Swept-wavelength lasers based on GaSb gain-chip technology for non-invasive biomedical sensing applications in the 1.7–2.5 μm wavelength range

No Thumbnail Available
Vizbaras, Augustinas
Šimonytė, Ieva
Miasojedovas, Arūnas
Trinkūnas, Augustinas
Bučiūnas, Tadas
Greibus, Mindaugas
Naujokaitė, Greta
Torcheboeuf, Nicolas
Droz, Serge
Boiko, Dmitri L.
The infrared spectral region beyond 1.7 μm is of utmost interest for biomedical applications due to strong overtone and combination absorption bands in a variety of important biomolecules such as lactates, urea, glucose, albumin, etc. In this article, we report on recent progress in widely tunable swept-wavelength lasers based on type-I GaSb gain-chip technology, setting a new state-of-the-art in the 1.7 – 2.5 μm range laser sources. We provide an application example for the spectroscopic sensing of several biomolecules in a cuvette as well as an experimental demonstration of a non-invasive in-vivo sensing of human serum albumin through the skin.
Publication Reference
Biomedical Optics Express, vol. 9 (10), pp. 4834-4849